Houston Methodist

Nanotechnology Approach for Targeted Inhalation Therapy of Lung Cancer

In developing a targeted inhalation therapy for lung cancer, Dr. Minko used the multi-tier targeted treatment approach that focused on suppression of all four types of  EGFR-TKs by a pool of siRNAs. It also included 1) induction of cell death by an  anticancer drug, 2) local inhalation delivery of therapeutic agents to the lungs (passive targeting), 3) active receptor-mediated targeting of the therapy specifically to cancer cells and 4) increasing the stability, solubility and cellular penetration  of siRNA and drug by nanoparticles. The application of the proposed approach demonstrated enhanced efficiency of the treatment of lung cancer and reduced  adverse side effects.

Presented by:
Tamara Minko, PhD
Distinguished Professor and Chair, Department of Pharmaceutics 
Ernest Mario School of Pharmacy
Rutgers, The State University of New Jersey

Thursday, October 24 at 3:00pm to 4:00pm

Houston Methodist Hospital, Walter Tower Columbia Conference Room (WT01-3018)
6565 Fannin Street

Event Type

Seminar

Category

Research

Attendance Options

In-Person

Website

http://attend.houstonmethodist.org

Department & Center
Department of Nanomedicine, Institute for Academic Medicine
Speaker

​​​​​​​Tamara Minko, PhD Distinguished Professor and Chair, Department of Pharmaceutics, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey

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