Houston Methodist

14th Annual Peggy and Gary Edwards Distinguished ALS Lecture: Rattling the Cage of Amyotrophic Lateral Sclerosis

Dominic B. Rowe, AM  
Professor of Neurology
Medicine and Health Sciences
Macquarie University
New South Wales, Australia

This lecture will share some of our recent achievements:

1. The genetic basis of ALS: After establishing the MND Research Centre at Macquarie University, we set about identifying new potential monogenic causes of ALS, in addition to genetic susceptibility in sporadic ALS. In addition, we have used methods to look at novel variations and differences between monozygotic twins to further understand the variables involved in disease onset and progression in sporadic ALS.

 2. New diagnostic methods in early ALS: Novel MRI methods with high sensitivity and specificity to identify cortical abnormalities in early ALS. 

3. Early phase therapeutic trials in ALS: We have completed two novel trials (Cu-ATSM and Triumeq) in ALS to determine safety and potential efficacy, both leading to much larger Phase 2 and 3 trials that are now underway.

Please note: This event is intended for the health professionals audience.


Friday, November 8, 2019 at 12:00pm to 1:00pm

Neurosensory Building, 1st Floor, Bluebird Auditorium

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Department & Center
Neurological Institute, Department of Neurology

Dominic B. Rowe, AM, Professor of Neurology, Faculty of Medicine and Health Sciences, Macquarie University, New South Wales, Australia

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