Engineering Strategies to Model and Treat Neurodegeneration

The Lippmann Lab is focused on modeling, understanding, and treating neurodegenerative disease by integrating concepts across engineering, neuroscience, and cellular and molecular biology. This research group leverages simple cell culture platforms, 3D engineered systems, human tissue, and in vivo models to study biological function, deconstruct mechanisms of disease, and develop engineered platforms, techniques and neurovascular treatment strategies that can be applied to basic wet lab research, model development, and drug delivery. Dr. Lippmann will highlight work developing complex models of vascularized human brain tissue, outline some of our emerging work on nonviral gene targeting, and discuss how the team envisions leveraging these efforts to combat Alzheimer’s disease, cerebral amyloid angiopathy, and tauopathies.

Monthly lecture series hosted by the Center for Neuroregeneration.