Houston Methodist

Cancer Diagnostics & Therapy with Aptamer Nanotechnology by Maxim V. Berezovski, PhD

Cancer-specific DNA aptamers can be developed and applied for tumor localization, margin assessment, circulating tumor cell detection and adjuvant treatment of cancer. Among the new aptamer nanotechnologies, Dr. Berezovski will discuss Aptamer-assisted Fluorescence-Guided Surgery (AptaFGS), a tumor-specific spray for glioblastoma neurosurgery that allows surgeons to immediately distinguish tumors from healthy tissues in a few simple steps without systematic administration into the circulatory system. He also presents Aptamer-guided MagnetoDynamic cell disruption (AptaMD), using a low frequency magnetic field that causes nanoparticles to oscillate and kill cancer cells without additional heating to save adjacent healthy cells and tissues. Berezovski’s study demonstrates the power of synthetic affinity ligands targeting tumors with opportunities for intraoperative tumor imaging and postoperative eradication of cancer cells.

Presented by:
Maxim V. Berezovski, PhD
Professor, Department of Chemistry & Biomolecular Sciences
Head, Bioanalytical & Molecular Interaction (BioAMI) Laboratory
Co-Director, Cellular Imaging & Cytometry Facility
Associate Director, John L. Holmes Mass Spectrometry Facility
University of Ottawa

Tuesday, February 18 at 12:00pm to 1:00pm

Houston Methodist Research Institute, Ernest H. Cockrell Boardroom (R2-311)
6670 Bertner Avenue

Event Type

Seminar

Category

Research

Attendance Options

In-Person

Website

http://attend.houstonmethodist.org

Department & Center
Cancer Center, Department of Nanomedicine, Cancer Research Program, Academic Institute
Speaker

Maxim V. Berezovski, PhD Professor, Department of Chemistry & Biomolecular Sciences Head, Bioanalytical & Molecular Interaction (BioAMI) Laboratory, Co-Director, Cellular Imaging & Cytometry Facility & Associate Director, John L. Holmes Mass Spectrometry Facility, University of Ottawa

Contact Email

cherrera2@houstonmethodist.org

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