Physicians and cytologists need the most up-to-date knowledge and strategies in pathology and cytopathology to provide the most appropriate ancillary testing for guiding patient management. Attendees will learn various new evidence-based reporting terminologies, which will enable them to assess the risk of malignancy, specifically regarding findings in thyroid, salivary, pancreas, biliary tract, and respiratory tract. By understanding these new site-specific reporting systems, attendees will know the risk of malignancy associated with each reporting category and appropriate ancillary testing and, therefore, better guide management of patients.