Hostile conditions in the tumor microenvironment provoke persistent endoplasmic reticulum (ER) stress in cancer cells and infiltrating immune cells. Aberrant activation of ER stress sensors and their downstream signaling pathways have emerged as key regulators of tumor growth, metastasis, and response to chemotherapy and immunotherapy. This talk will discuss the physiological inducers of ER stress in the tumor milieu and the profound immunomodulatory effects of sustained ER stress responses in cancer hosts.
Streamed Online via MS Teams
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Thursday, March 25 at 10:00am to 11:00amVirtual Event