Dr. McCullough's research focuses on understanding sex differences in ischemic cell death; age-related inflammation; and social factors in stroke recovery. Basic molecular and animal studies in males and females have direct translational relevance, as treatments have revealed the efficacy in one sex has paradoxically shown a detrimental effect in the other sex—increasingly recognized in clinical stroke populations. McCullough’s research also explores the genetic and hormonal differences in inflammation across the life span. Her lab investigates the role of inflammation in stroke recovery, with current studies manipulating age-related inflammation using bone marrow transplants, parabiosis and microbiome transfers. Factors such as depression and social isolation dramatically impact recovery and mortality in stroke patients. For depression, mechanisms under investigation include microRNA regulation of microglia and microbiome alterations.
Louise D. McCullough, MD, PhD
Professor and Chair, Department of Neurology
Roy M. and Phyllis Gough Huffington Distinguished Chair
Chief of Neurology Service, Memorial Hermann Hospital - Texas Medical Center
This event will be streamed online via Microsoft Teams.
Hosted by the Center for Neuroregeneration, Department of Neurosurgery
+1 832-856-3689 United States, Houston (Toll)
Conference ID: 785 014 55#
Tuesday, September 29 at 10:00am to 11:30amVirtual Event