The Yun laboratory studies cell-intrinsic and -extrinsic factors that regulate tumor progression and immune evasion in glioblastoma and medulloblastoma.  Our goals are to elucidate mechanisms that regulate brain cancer stem cells and identify critical signaling nodes among cancer and non-cancer cells (such as immune cells) that promote tumor progression, immune evasion, and therapy resistance. Kyuson Yun, PhD, will describe our recent progress in elucidating the cellular heterogeneity of human GBM at the single-cell level and the roles of S100A4 and YAP1 as multi-functional regulators of brain cancer stem cells, immune suppression, and sex-bias in brain tumor incidence and treatment response. 

In-person attendance at the Ernest H. Cockrell Boardroom (R2-311) is limited to 20 attendees. This seminar will also be streamed online via Microsoft Teams