ISAC 2026 advances critical care beyond one-size-fits-all by utilizing dynamic physiologic data, advanced patient monitoring, and analytics with the goal to deliver the right intervention to the right patient at the right time: Precision and Personalization in Critical Care. Because critical illness is systemic, precision demands collaboration across pulmonary/critical care, anesthesia, surgery and transplant, cardiovascular critical care, neurocritical care, pharmacy, nursing/APPs, RTs, PTs, and palliative care. Over the course of 2-days, through expert presentations, focused panels, case-based discussions, and 6 hands-on workshops, participants will learn latest practice-ready pathways for glycemic control, brain death diagnosis, anticoagulation & transfusion stewardship, delirium, music therapy, trauma-informed care, AI in action, and perioperative optimization to post-ICU recovery.